A SYNTHESIS OF THE MICRO-NANO PLASTIC WASTE IMPACT ON HUMAN HEALTH. A MEDICAL PERSPECTIVE

Dana PERNIU, Liliana ROGOZEA, Anca DRAGHICI, Anja BUBIK, Katrin ŠKOLNIK ŠKRABE

Abstract


This article presents a comprehensive synthesis of recent scientific findings on the ecological and medical impacts of micro- and nano-plastic (MNP) pollution. It highlights the pervasive presence of MNPs in the environment and their infiltration into human body through inhalation, ingestion, dermal contact, and even prenatal exposure. The study outlines the toxicological effects of plastic particles and additives, linking them to various health disorders such as endocrine disruption, respiratory and gastrointestinal illnesses, cancer, neurological and cardiovascular diseases, and immune dysfunctions. The paper also describes the challenges posed by MNPs on 12 of the Sustainable Development Goals (SDGs), emphasizing the need for systemic solutions including stricter regulations, circular economy practices, and public awareness initiatives. The research is part of the EDU4PlastiCircular project, aiming to foster education and action toward a climate-neutral and plastic-responsible future.

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References


United Nations Environment Programme, From Pollution to Solution: A global assessment of marine litter and plastic pollution. Nairobi, https://leap.unep.org/en/ countries/case-studies/european-union-legal-frameworks, 2021.

Nikiema, J., Mateo-Sagasta, J., Asiedu, Z., Saad, D., Lamizana, B., Water pollution by plastics and microplastics: a review of technical solutions from source to sea, https://cgspace.cgiar.org/server/api/core/bitstreams/a1a15a9e-3ac9-4f39-9b22-017624173656/content, 2024.

Allen, D., Allen, S., Abbasi, S., Baker, A., Bergmann, M., Brahney, J., ... Wright, S. Microplastics and nanoplastics in the marine-atmosphere environment. Nature Reviews Earth & Environment, 3(6), pp. 393-405, 2022.

Walker, T. R., (Micro) plastics and the UN sustainable development goals, Current Opinion in Green and Sustainable Chemistry, 30, 100497, 2021.

Li, Y., Chen, L., Zhou, N., Chen, Y., Ling, Z., Xiang, P., Microplastics in the human body: A comprehensive review of exposure, distribution, migration mechanisms, and toxicity, Science of the Total Environment, 174215, 2024.

Enyoh, C. E., Devi, A., Kadono, H., Wang, Q., Rabin, M. H., The plastic within: microplastics invading human organs and bodily fluids systems, Environments, 10(11), 194, 2023.

Wu, P., Lin, S., Cao, G., Wu, J., Jin, H., Wang, C., Cai, Z., Absorption, distribution, metabolism, excretion and toxicity of microplastics in the human body and health implications, Journal of Hazardous Materials, 437, 129361, 2022.

Morales-Cano, K. L., Pena-Montes, C., Hermida-Castellanos, L., Pelaez, L. A. P., Adame-Adame, C. M., Micro (Nano) Plastics as carriers of toxic agents and their impact on human health. 2023. https://www.intechopen.com/chapters/87700

Thaler S., “Forever chemicals” in microplastics spark over $250B a year health crisis: study, Published Jan. 11, https://nypost.com/2024/01/11/business/microplastics-cost-us-250b-more-than-entire-covid-pandemic-study/, 2024.

UN Environment Program, Historic day in the campaign to beat plastic pollution: Nations commit to develop a legally binding agreement, https://www.unep.org/news-and-stories/press-release/historic-day-campaign-beat-plastic-pollution-nations-commit-develop

European Union - Legal Frameworks, https://leap.unep.org/en/countries/case-studies/european-union-legal-frameworks

Plastics Europe, How plastics are made https://plasticseurope.org/plastics-explained/how-plastics-are-made/ (Access 14-06-2025).

European Environment Agency, Plastics, (Published Nov. 2024), https://www.eea.europa.eu/en/topics/in-depth/plastics

Pironti, C., Ricciardi, M., Motta, O., Miele, Y., Proto, A., Montano, L., Microplastics in the environment: intake through the food web, human exposure and toxicological effects, Toxics, 9(9), 224, 2021.

Liu, Y., Cao, Y., Li, H., Liu, H., Bi, L., Chen, Q., Peng, R., A systematic review of microplastics emissions in kitchens: Understanding the links with diseases in daily life, Environment international, 188, 108740, 2024.

Yu, R.S., Singh, S., Microplastic pollution: threats and impacts on global marine ecosystems. Sustainability, 15(17), 13252, 2023.

Karasik, R., Lauer, N.E., Baker, A.E., Lisi, N. E., Somarelli, J.A., Eward, W.C., Dunphy-Daly, M.M., Inequitable distribution of plastic benefits and burdens on economies and public health. Frontiers in Marine Science, 9, 1017247, 2020.

Kumar, M., Xiong, X., He, M., Tsang, D.C., Gupta, J., Khan, E., Bolan, N.S., Microplastics as pollutants in agricultural soils. Environmental Pollution, 265, 114980, 2020.

Ragusa, A., Svelato, A., Santacroce, C., Catalano, P., Notarstefano, V., Carnevali, O., Giorgini, E. Plasticenta: First evidence of microplastics in human placenta. Environment international, 146, 106274, 2021.

Vethaak, A.D., Legler, J., Microplastics and human health. Science, 371(6530), pp. 672-674, 2021, 2021.

Yaman, C., Anil, I., Alagha, O., Potential for greenhouse gas reduction and energy recovery from MSW through different waste management technologies. Journal of Cleaner Production, 264, 121432, 2020.

Yang, L., Wang, X.C., Dai, M., Chen, B., Qiao, Y., Deng, H., Wang, Y., Shifting from fossil-based economy to bio-based economy: Status quo, challenges, and prospects. Energy, 228, 120533, 2021.

Suarez, A., Ford, E., Venditti, R., Kelley, S., Saloni, D., Gonzalez, R., Rethinking the use of bio-based plastics to accelerate the decarbonization of our society. Resources, Conservation and Recycling, 186, 106593, 2022.

Zhou, G., Zhang, H., Su, Z., Zhang, X., Zhou, H., Yu, L., Wang, X., A biodegradable, waterproof, and thermally processable cellulosic bioplastic enabled by dynamic covalent modification. Advanced Materials, 35(25), 2301398, 2023.

Arora, Y., Sharma, S., Sharma, V., Microalgae in bioplastic production: a comprehensive review. Arabian Journal for Science and Engineering, 48(6), pp. 7225-7241, 2023.

Liu, Z., Adams, M., Walker, T.R., Are exports of recyclables from developed to developing countries waste pollution transfer or part of the global circular economy? Resources, Conservation and Recycling, 136, pp. 22-23, 2018.

Law, K.L., Starr, N., Siegler, T.R., Jambeck, J.R., Mallos, N.J., Leonard, G.H., The United States’ contribution of plastic waste to land and ocean. Science advances, 6(44), 2020.

Zhu, X. The plastic cycle–an unknown branch of the carbon cycle. Frontiers in Marine Science, 7, 609243, 2021.

Benavides, P.T., Lee, U., Zarè-Mehrjerdi, O., Life cycle greenhouse gas emissions and energy use of polylactic acid, bio-derived polyethylene, and fossil-derived polyethylene. Journal of Cleaner Production, 277, 124010, 2020.

Gündoğdu, S., Mihai, F.C., Fischer, E.K., Blettler, M.C., Turgay, O.C., Akça, M.O., Ayat, B., Micro and nano plastics in groundwater systems: a review of current knowledge and future perspectives. TrAC Trends in Analytical Chemistry, 165, 117119, 2023.

Maddela, N.R., Ramakrishnan, B., Kadiyala, T., Venkateswarlu, K., Megharaj, M., Do microplastics and nanoplastics pose risks to biota in agricultural ecosystems? Soil Systems, 7(1), 19, 2023.

EDU4PlastiCircular project, https://microplastics.today/


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